Gene expression profiling of brakeless mutant Drosophila embryos
نویسندگان
چکیده
منابع مشابه
Gene expression profiling of brakeless mutant Drosophila embryos
The transcriptional co-regulator Brakeless performs many important functions during Drosophila development, but few target genes have been identified. Here we use Affymetrix microarrays to identify Brakeless-regulated genes in 2-4 h old Drosophila embryos. Robust multi-array analysis (RMA) and statistical tests revealed 240 genes that changed their expression more than 1.5 fold. We find that up...
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Complex gene expression patterns in animal development are generated by the interplay of transcriptional activators and repressors at cis-regulatory DNA modules (CRMs). How repressors work is not well understood, but often involves interactions with co-repressors. We isolated mutations in the brakeless gene in a screen for maternal factors affecting segmentation of the Drosophila embryo. Brakel...
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1 Institute for Data Analysis and Visualization, University of California, Davis, 1 Shields Avenue, Davis CA 95616, USA {myhuang,oruebel,bhamann}@ucdavis.edu 2 International Research Training Group “Visualization of Large and Unstructured Data Sets,” University of Kaiserslautern, Germany [email protected] 3 Visualiztion Group, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Be...
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ژورنال
عنوان ژورنال: Data in Brief
سال: 2015
ISSN: 2352-3409
DOI: 10.1016/j.dib.2015.08.033